diff --git a/extmod/extmod.mk b/extmod/extmod.mk
index 2207c21f0d..c2298bc521 100644
--- a/extmod/extmod.mk
+++ b/extmod/extmod.mk
@@ -527,6 +527,7 @@ ifeq ($(MICROPY_PY_OPENAMP),1)
 OPENAMP_DIR = lib/open-amp
 LIBMETAL_DIR = lib/libmetal
 GIT_SUBMODULES += $(LIBMETAL_DIR) $(OPENAMP_DIR)
+MICROPY_PY_OPENAMP_MODE ?= 0
 include $(TOP)/extmod/libmetal/libmetal.mk
 
 INC += -I$(TOP)/$(OPENAMP_DIR)
@@ -536,12 +537,21 @@ ifeq ($(MICROPY_PY_OPENAMP_REMOTEPROC),1)
 CFLAGS += -DMICROPY_PY_OPENAMP_REMOTEPROC=1
 endif
 
+ifeq ($(MICROPY_PY_OPENAMP_MODE),0)
+CFLAGS += -DMICROPY_PY_OPENAMP_HOST=1
+CFLAGS_THIRDPARTY += -DVIRTIO_DRIVER_ONLY
+else ifeq ($(MICROPY_PY_OPENAMP_MODE),1)
+CFLAGS += -DMICROPY_PY_OPENAMP_DEVICE=1
+CFLAGS_THIRDPARTY += -DVIRTIO_DEVICE_ONLY
+else
+$(error Invalid Open-AMP mode specified: $(MICROPY_PY_OPENAMP_MODE))
+endif
+
 CFLAGS_THIRDPARTY += \
     -I$(BUILD)/openamp \
     -I$(TOP)/$(OPENAMP_DIR) \
     -I$(TOP)/$(OPENAMP_DIR)/lib/include/ \
     -DMETAL_INTERNAL \
-    -DVIRTIO_DRIVER_ONLY \
     -DNO_ATOMIC_64_SUPPORT \
     -DRPMSG_BUFFER_SIZE=512 \
 
diff --git a/extmod/modopenamp.c b/extmod/modopenamp.c
index 29135d57a8..a10441d64a 100644
--- a/extmod/modopenamp.c
+++ b/extmod/modopenamp.c
@@ -52,11 +52,20 @@
 
 #if MICROPY_PY_OPENAMP_RSC_TABLE_ENABLE
 #define VIRTIO_DEV_ID           0xFF
+#if MICROPY_PY_OPENAMP_HOST
+#define VIRTIO_DEV_ROLE         RPMSG_HOST
+#else
+#define VIRTIO_DEV_ROLE         RPMSG_REMOTE
+#endif // MICROPY_PY_OPENAMP_HOST
 #define VIRTIO_DEV_FEATURES     (1 << VIRTIO_RPMSG_F_NS)
 
 #define VRING0_ID               0   // VRING0 ID (host to remote) fixed to 0 for linux compatibility
 #define VRING1_ID               1   // VRING1 ID (remote to host) fixed to 1 for linux compatibility
+#if MICROPY_PY_OPENAMP_HOST
 #define VRING_NOTIFY_ID         VRING0_ID
+#else
+#define VRING_NOTIFY_ID         VRING1_ID
+#endif // MICROPY_PY_OPENAMP_HOST
 
 #define VRING_COUNT             2
 #define VRING_ALIGNMENT         32
@@ -71,13 +80,15 @@
 #define VRING_BUFF_ADDR         (METAL_SHM_ADDR + 0x2000)
 #define VRING_BUFF_SIZE         (METAL_SHM_SIZE - 0x2000)
 
+#if MICROPY_PY_OPENAMP_HOST
 static const char openamp_trace_buf[128];
 #define MICROPY_PY_OPENAMP_TRACE_BUF       ((uint32_t)openamp_trace_buf)
 #define MICROPY_PY_OPENAMP_TRACE_BUF_LEN   sizeof(MICROPY_PY_OPENAMP_TRACE_BUF)
+#endif // MICROPY_PY_OPENAMP_HOST
 
 #endif // MICROPY_PY_OPENAMP_RSC_TABLE_ENABLE
 
-#if MICROPY_PY_OPENAMP_REMOTEPROC
+#if MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_REMOTEPROC
 extern mp_obj_type_t openamp_remoteproc_type;
 #endif
 
@@ -267,12 +278,11 @@ static void openamp_ns_callback(struct rpmsg_device *rdev, const char *name, uin
     }
 }
 
-#if MICROPY_PY_OPENAMP_RSC_TABLE_ENABLE
+#if MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_RSC_TABLE_ENABLE
 // The shared resource table must be initialized manually by the host here,
 // because it's not located in the data region, so the startup code doesn't
 // know about it.
-static void openamp_rsc_table_init(openamp_rsc_table_t **rsc_table_out) {
-    openamp_rsc_table_t *rsc_table = METAL_RSC_ADDR;
+static void openamp_rsc_table_init(openamp_rsc_table_t *rsc_table) {
     memset(rsc_table, 0, METAL_RSC_SIZE);
 
     rsc_table->version = 1;
@@ -299,9 +309,8 @@ static void openamp_rsc_table_init(openamp_rsc_table_t **rsc_table_out) {
     // Flush resource table.
     metal_cache_flush((uint32_t *)rsc_table, sizeof(openamp_rsc_table_t));
     #endif
-    *rsc_table_out = rsc_table;
 }
-#endif // MICROPY_PY_OPENAMP_RSC_TABLE_ENABLE
+#endif // MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_RSC_TABLE_ENABLE
 
 static mp_obj_t openamp_new_service_callback(mp_obj_t ns_callback) {
     if (MP_STATE_PORT(virtio_device) == NULL) {
@@ -342,8 +351,10 @@ void openamp_init(void) {
     metal_init(&metal_params);
 
     // Initialize the shared resource table.
-    openamp_rsc_table_t *rsc_table;
-    openamp_rsc_table_init(&rsc_table);
+    openamp_rsc_table_t *rsc_table = METAL_RSC_ADDR;
+    #if MICROPY_PY_OPENAMP_HOST
+    openamp_rsc_table_init(rsc_table);
+    #endif // MICROPY_PY_OPENAMP_HOST
 
     if (metal_register_generic_device(&shm_device) != 0) {
         mp_raise_msg(&mp_type_OSError, MP_ERROR_TEXT("Failed to register metal device"));
@@ -368,7 +379,7 @@ void openamp_init(void) {
     }
 
     // Create virtio device.
-    struct virtio_device *vdev = rproc_virtio_create_vdev(RPMSG_HOST, VIRTIO_DEV_ID,
+    struct virtio_device *vdev = rproc_virtio_create_vdev(VIRTIO_DEV_ROLE, VIRTIO_DEV_ID,
         &rsc_table->vdev, rsc_io, NULL, metal_rproc_notify, NULL);
     if (vdev == NULL) {
         mp_raise_msg(&mp_type_OSError, MP_ERROR_TEXT("Failed to create virtio device"));
@@ -389,8 +400,8 @@ void openamp_init(void) {
     // The remote processor detects that the virtio device is ready by polling
     // the status field in the resource table.
     rpmsg_virtio_init_shm_pool(&virtio_device->shm_pool, (void *)VRING_BUFF_ADDR, (size_t)VRING_BUFF_SIZE);
-    rpmsg_init_vdev(&virtio_device->rvdev, vdev, openamp_ns_callback, shm_io, &virtio_device->shm_pool);
 
+    rpmsg_init_vdev(&virtio_device->rvdev, vdev, openamp_ns_callback, shm_io, &virtio_device->shm_pool);
     MP_STATE_PORT(virtio_device) = virtio_device;
 }
 
@@ -399,7 +410,7 @@ static const mp_rom_map_elem_t globals_dict_table[] = {
     { MP_ROM_QSTR(MP_QSTR_ENDPOINT_ADDR_ANY), MP_ROM_INT(RPMSG_ADDR_ANY) },
     { MP_ROM_QSTR(MP_QSTR_new_service_callback), MP_ROM_PTR(&openamp_new_service_callback_obj) },
     { MP_ROM_QSTR(MP_QSTR_Endpoint), MP_ROM_PTR(&endpoint_type) },
-    #if MICROPY_PY_OPENAMP_REMOTEPROC
+    #if MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_REMOTEPROC
     { MP_ROM_QSTR(MP_QSTR_RemoteProc), MP_ROM_PTR(&openamp_remoteproc_type) },
     #endif
 };
diff --git a/extmod/modopenamp_remoteproc.c b/extmod/modopenamp_remoteproc.c
index 82719dca96..ed61cb6bd4 100644
--- a/extmod/modopenamp_remoteproc.c
+++ b/extmod/modopenamp_remoteproc.c
@@ -26,7 +26,7 @@
  * OpenAMP's remoteproc class.
  */
 
-#if MICROPY_PY_OPENAMP_REMOTEPROC
+#if MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_REMOTEPROC
 
 #include "py/obj.h"
 #include "py/nlr.h"
@@ -170,4 +170,4 @@ MP_DEFINE_CONST_OBJ_TYPE(
     locals_dict, &openamp_remoteproc_dict
     );
 
-#endif // MICROPY_PY_OPENAMP_REMOTEPROC
+#endif // MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_REMOTEPROC
diff --git a/extmod/modopenamp_remoteproc_store.c b/extmod/modopenamp_remoteproc_store.c
index aed652c485..03022ebc83 100644
--- a/extmod/modopenamp_remoteproc_store.c
+++ b/extmod/modopenamp_remoteproc_store.c
@@ -26,7 +26,7 @@
  * OpenAMP's remoteproc store.
  */
 
-#if MICROPY_PY_OPENAMP_REMOTEPROC
+#if MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_REMOTEPROC
 
 #include "py/obj.h"
 #include "py/nlr.h"
@@ -141,4 +141,4 @@ const struct image_store_ops openamp_remoteproc_store_ops = {
 
 #endif // MICROPY_PY_OPENAMP_REMOTEPROC_STORE_ENABLE
 
-#endif // MICROPY_PY_OPENAMP_REMOTEPROC
+#endif // MICROPY_PY_OPENAMP_HOST && MICROPY_PY_OPENAMP_REMOTEPROC